L. Ségalat : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (53)
Les plus populaires
Liste
- Liste
- Tableau

1

Invertebrate Animal Models of Diseases as Screening Tools in Drug Discovery

Ségalat, Laurent

Journal:

ACS Chemical Biology

Année:

2007

Langue:

english

Fichier:

PDF, 418 KB

english, 2007

2

CAPON expression in skeletal muscle is regulated by position, repair, NOS activity, and dystrophy

Laurent Ségalat, Karine Grisoni, Jonathan Archer, Cinthya Vargas, Anne Bertrand, Judy E. Anderson

Journal:

Experimental Cell Research

Année:

2005

Langue:

english

Fichier:

PDF, 670 KB

english, 2005

3

Loss-of-function genetic diseases and the concept of pharmaceutical targets

Laurent Ségalat

Journal:

Orphanet Journal of Rare Diseases

Année:

2007

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2007

4

Dystrobrevin requires a dystrophin-binding domain to function in Caenorhabditis elegans

Karine Grisoni, Kathrin Gieseler, Laurent Ségalat

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 193 KB

english, 2002

5

Mutations in the Caenorhabditis elegans dystrophin-like gene dys-1 lead to hyperactivity and suggest a link with cholinergic transmission

Catherine Bessou, Jean-Bernard Giugia, Christopher J. Franks, Lindy Holden-Dye, L. Ségalat

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 642 KB

english, 1998

6

Dystrobrevin- and dystrophin-like mutants display similar phenotypes in the nematode Caenorhabditis elegans

Kathrin Gieseler, Catherine Bessou, L. Ségalat

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 150 KB

english, 1999

7

Characterization of theCaenorhabditis elegansG protein-coupled serotonin receptors

Maïté Carre-Pierrat, David Baillie, Robert Johnsen, Rhonda Hyde, Anne Hart, Laure Granger, Laurent Ségalat

Journal:

Invertebrate Neuroscience

Année:

2006

Langue:

english

Fichier:

PDF, 502 KB

english, 2006

8

Blocking of Striated Muscle Degeneration by Serotonin inC. elegans

Maité Carre-Pierrat, Marie-Christine Mariol, Lucie Chambonnier, Aurélie Laugraud, Fabienne Heskia, Jean Giacomotto, Laurent Ségalat

Journal:

Journal of Muscle Research and Cell Motility

Année:

2006

Langue:

english

Fichier:

PDF, 187 KB

english, 2006

9

TheC. elegansdense body: anchoring and signaling structure of the muscle

Claire Lecroisey, Laurent Ségalat, Kathrin Gieseler

Journal:

Journal of Muscle Research and Cell Motility

Année:

2007

Langue:

english

Fichier:

PDF, 346 KB

english, 2007

10

Description of International Caenorhabditis elegans Experiment first flight (ICE-FIRST)

N.J. Szewczyk, J. Tillman, C.A. Conley, L. Granger, L. Segalat, A. Higashitani, S. Honda, Y. Honda, H. Kagawa, R. Adachi, A. Higashibata, N. Fujimoto, K. Kuriyama, N. Ishioka, K. Fukui, D. Baillie, A.

Journal:

Advances in Space Research

Année:

2008

Langue:

english

Fichier:

PDF, 361 KB

english, 2008

11

Pyruvate imbalance mediates metabolic reprogramming and mimics lifespan extension by dietary restriction in Caenorhabditis elegans

Laurent Mouchiroud, Laurent Molin, Prasad Kasturi, Mohamed N. Triba, Marc Emmanuel Dumas, Marieangela C. Wilson, Andrew P. Halestrap, Damien Roussel, Ingrid Masse, Nicolas Dallière, Laurent Ségalat, M

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 956 KB

english, 2011

12

High-throughput screening and small animal models, where are we?

Jean Giacomotto, Laurent Ségalat

Journal:

British Journal of Pharmacology

Année:

2010

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2010

13

System crash

Ségalat, Laurent

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 261 KB

english, 2010

14

Loss-of-function genetic diseases and the concept of pharmaceutical targets

Journal:

Nature Reviews Genetics

Année:

2007

Langue:

english

Fichier:

PDF, 207 KB

english, 2007

15

Duchenne Muscular Dystrophy: Stalled at the junction?

Ségalat, Laurent, Anderson, Judy E

Journal:

European Journal of Human Genetics

Année:

2004

Langue:

english

Fichier:

PDF, 45 KB

english, 2004

16

Characterization of K+ currents using an in situ patch clamp technique in body wall muscle cells from Caenorhabditis elegans

Maëlle Jospin, Marie-Christine Mariol, Laurent Ségalat, Bruno Allard

Journal:

The Journal of Physiology

Année:

2002

Langue:

english

Fichier:

PDF, 378 KB

english, 2002

17

Patch clamp study of the UNC-105 degenerin and its interaction with the LET-2 collagen in Caenorhabditis elegans muscle

Maëlle Jospin, Marie-Christine Mariol, Laurent Segalat, Bruno Allard

Journal:

The Journal of Physiology

Année:

2004

Langue:

english

Fichier:

PDF, 528 KB

english, 2004

18

Genetic suppression of phenotypes arising from mutations in dystrophin-related genes in Caenorhabditis elegans

Kathrin Gieseler, Karine Grisoni, Laurent Ségalat

Journal:

Current Biology

Année:

2000

Langue:

english

Fichier:

PDF, 85 KB

english, 2000

19

Muscular degeneration in the absence of dystrophin is a calcium-dependent process

Marie-Christine Mariol, Laurent Ségalat

Journal:

Current Biology

Année:

2001

Langue:

english

Fichier:

PDF, 120 KB

english, 2001

20

Molecular, genetic and physiological characterisation of dystrobrevin-like (dyb-1) mutants of Caenorhabditis elegans

Kathrin Gieseler, Marie-Christine Mariol, Catherine Bessou, Martine Migaud, Christopher J Franks, Lindy Holden-Dye, Laurent Ségalat

Journal:

Journal of Molecular Biology

Année:

2001

Langue:

english

Fichier:

PDF, 364 KB

english, 2001

21

The stn-1 Syntrophin Gene of C. elegans is Functionally Related to Dystrophin and Dystrobrevin

Karine Grisoni, Kathrin Gieseler, Marie-Christine Mariol, Edwige Martin, Maité Carre-Pierrat, Gary Moulder, Robert Barstead, Laurent Ségalat

Journal:

Journal of Molecular Biology

Année:

2003

Langue:

english

Fichier:

PDF, 568 KB

english, 2003

22

The SLO-1 BK Channel of Caenorhabditis elegans is Critical for Muscle Function and is Involved in Dystrophin-dependent Muscle Dystrophy

Maité Carre-Pierrat, Karine Grisoni, Kathrin Gieseler, Marie-Christine Mariol, Edwige Martin, Maelle Jospin, Bruno Allard, Laurent Ségalat

Journal:

Journal of Molecular Biology

Année:

2006

Langue:

english

Fichier:

PDF, 565 KB

english, 2006

23

Prednisone reduces muscle degeneration in dystrophin-deficient Caenorhabditis elegans

Aurélie Gaud, Jean-Marc Simon, Thomas Witzel, Maité Carre-Pierrat, Camille G Wermuth, Laurent Ségalat

Journal:

Neuromuscular Disorders

Année:

2004

Langue:

english

Fichier:

PDF, 208 KB

english, 2004

24

Reply to de Luca

Journal:

Neuromuscular Disorders

Année:

2004

Langue:

english

Fichier:

PDF, 35 KB

english, 2004

25

G.P.5 08 Dystrophin-dependent muscle degeneration requires a fully functional contractile machinery to occur in Caenorhabditis elegans

M.C. Mariol, L. Ségalat

Journal:

Neuromuscular Disorders

Année:

2006

Langue:

english

Fichier:

PDF, 44 KB

english, 2006

26

Dystrophin-dependent muscle degeneration requires a fully functional contractile machinery to occur in C. elegans

Marie-Christine Mariol, Edwige Martin, Lucie Chambonnier, Laurent Ségalat

Journal:

Neuromuscular Disorders

Année:

2007

Langue:

english

Fichier:

PDF, 360 KB

english, 2007

27

T.P.4.12 Carbonic anhydrase inhibitors’ therapeutic effects on dystrophin-deficient mouse muscle

C.P. Pertl, L.S. Segalat, H.L. Lochmueller, C.T. Thirion

Journal:

Neuromuscular Disorders

Année:

2008

Langue:

english

Fichier:

PDF, 45 KB

english, 2008

28

T.P.2.02 Effect of 20 approved drugs on a wide range of mdx parameters

M. Carre-Pierrat, A. Lafoux, F. Fougerousse, C. Huchet-Cadiou, L. Ségalat

Journal:

Neuromuscular Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 41 KB

english, 2009

29

T.P.2.01 Assessment of treatment efficiency using the mdx model: How to interpret the data?

M. Carre-Pierrat, L. Ségalat, L. Ségalat

Journal:

Neuromuscular Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 41 KB

english, 2009

30

G.P.13.01 DYC-1 and ZYX-1, new actors of muscle degeneration in Caenorhabditis elegans

C. Lecroisey, M.C. Mariol, Y. Schwab, M. Labouesse, L. Ségalat, K. Gieseler

Journal:

Neuromuscular Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 43 KB

english, 2009

31

Pre-clinical study of 21 approved drugs in the mdx mouse

Maïté Carre-Pierrat, Aude Lafoux, Guillaume Tanniou, Lucie Chambonnier, Alexandra Divet, Francoise Fougerousse, Corinne Huchet-Cadiou, Laurent Ségalat

Journal:

Neuromuscular Disorders

Année:

2011

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2011

32

Gene expression profiling studies on Caenorhabditis elegans dystrophin mutants dys-1(cx-35) and dys-1(cx18)

Paula R. Towers, Pascal Lescure, Dilair Baban, Julie A. Malek, Jose Duarte, Emma Jones, Kay E. Davies, Laurent Ségalat, David B. Sattelle

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 970 KB

english, 2006

33

Caenorhabditis elegans as a chemical screening tool for the study o f neuromuscular disorders. Manual and semi-automated methods

Jean Giacomotto, Laurent Ségalat, Maïté Carre-Pierrat, Kathrin Gieseler

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 896 KB

english, 2012

34

In vitro interactions of Caenorhabditis elegans dystrophin with dystrobrevin and syntrophin

Kathrin Gieseler, Manal Abdel-Dayem, Laurent Ségalat

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 188 KB

english, 1999

35

Mutations in the dystrophin-like dys-1 gene of Caenorhabditis elegans result in reduced acetylcholinesterase activity

Jean-Bernard Giugia, Kathrin Gieseler, Martine Arpagaus, Laurent Ségalat

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 81 KB

english, 1999

36

Genetic evidence for a dystrophin-glycoprotein complex (DGC) in Caenorhabditis elegans

Karine Grisoni, Edwige Martin, Kathrin Gieseler, Marie-Christine Mariol, Laurent Ségalat

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 554 KB

english, 2002

37

Serotonin Inhibition of Synaptic Transmission: Gαo Decreases the Abundance of UNC-13 at Release Sites

Stephen Nurrish, Laurent Ségalat, Joshua M. Kaplan

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 242 KB

english, 1999

38

Overexpression of dystrobrevin delays locomotion defects and muscle degeneration in a dystrophin-deficient Caenorhabditis elegans

Kathrin Gieseler, Karine Grisoni, Marie-Christine Mariol, Laurent Ségalat

Journal:

Neuromuscular Disorders

Année:

2002

Langue:

english

Fichier:

PDF, 287 KB

english, 2002

39

Dystrophin and functionally related proteins in the nematode Caenorhabditis elegans

Laurent Ségalat

Journal:

Neuromuscular Disorders

Année:

2002

Langue:

english

Fichier:

PDF, 168 KB

english, 2002

40

Spatial distribution of the Sm antigen in Drosophila early embryos

Ségalat, L, Lepesant, JA

Journal:

Biology of the Cell

Année:

1992

Langue:

english

Fichier:

PDF, 13.24 MB

english, 1992

41

Dissection of the Drosophila pourquoi-pas? promoter: Complex ovarian expression is driven by distinct follicle cell- and germ line-specific enhancers

Ségalat, Laurent, Berger, Guillemette, Lepesant, Jean-Antoine

Journal:

Mechanisms of Development

Année:

1994

Langue:

english

Fichier:

PDF, 2.01 MB

english, 1994

42

Drug Discovery: Here Comes the Worm

Ségalat, Laurent

Journal:

ACS Chemical Biology

Année:

2006

Langue:

english

Fichier:

PDF, 138 KB

english, 2006

43

Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy

Giacomotto, J., Brouilly, N., Walter, L., Mariol, M.-C., Berger, J., Segalat, L., Becker, T. S., Currie, P. D., Gieseler, K.

Journal:

Human Molecular Genetics

Année:

2013

Langue:

english

Fichier:

PDF, 2.73 MB

english, 2013

44

Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans

Segalat, L., Elkes, D., Kaplan, J.

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 1.54 MB

english, 1995

45

Metabotyping of Caenorhabditis elegans reveals latent phenotypes

Blaise, B. J., Giacomotto, J., Elena, B., Dumas, M.-E., Toulhoat, P., Segalat, L., Emsley, L.

Journal:

Proceedings of the National Academy of Sciences

Année:

2007

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2007

46

DYC-1, a Protein Functionally Linked to Dystrophin in Caenorhabditis elegans Is Associated with the Dense Body, Where It Interacts with the Muscle LIM Domain Protein ZYX-1

Lecroisey, C., Martin, E., Mariol, M.-C., Granger, L., Schwab, Y., Labouesse, M., Segalat, L., Gieseler, K.

Journal:

Molecular Biology of the Cell

Année:

2007

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2007

47

The Drosophila pourquoi-pas?/wings-down zinc finger protein: oocyte nucleus localization and embryonic requirement.

Segalat, L, Perichon, R, Bouly, J P, Lepesant, J A

Journal:

Genes & Development

Année:

1992

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1992

48

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy

Giacomotto, J., Pertl, C., Borrel, C., Walter, M. C., Bulst, S., Johnsen, B., Baillie, D. L., Lochmuller, H., Thirion, C., Segalat, L.

Journal:

Human Molecular Genetics

Année:

2009

Langue:

english

Fichier:

PDF, 587 KB

english, 2009

49

ZYX-1, the unique zyxin protein of Caenorhabditis elegans, is involved in dystrophin-dependent muscle degeneration

Lecroisey, C., Brouilly, N., Qadota, H., Mariol, M.-C., Rochette, N. C., Martin, E., Benian, G. M., Segalat, L., Mounier, N., Gieseler, K.

Journal:

Molecular Biology of the Cell

Année:

2013

Langue:

english

Fichier:

PDF, 4.00 MB

english, 2013

50

The L-Type Voltage-Dependent Ca2+Channel EGL-19 Controls Body Wall Muscle Function in Caenorhabditis elegans

Maëlle Jospin, Vincent Jacquemond, Marie-Christine Mariol, Laurent Ségalat and Bruno Allard

Journal:

The Journal of Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 2.24 MB

english, 2002